Truth 1: Alcohol addiction from 2 parts per thousand disguises the pain
The main nervous system (CNS) is a crucial target organ of alcohol.
Alcohol comes as a small molecule through each cell wall of the body, is rapidly taken in and rapidly dispersed in the body. For more detail go to this article.
After drinking alcohol, it is currently soaked up in the mouth and throat area.
The primary part, however, is absorbed by the body in the stomach and small intestine.
How rapidly alcohol is soaked up and therefore likewise establishes its pain-relieving result depends on whether you have actually consumed previously, along with the kind of alcohol.
Carbonated drinks, such as sparkling wine, speed up alcohol consumption, as they mechanically irritate the stomach and intestinal wall and promote the blood circulation of the mucous membrane.
Scientific studies have revealed that alcohol attacks particular neuronal locations.
This involves so-called receptors and signaling pathways of neurotransmitters.
Alcohol triggers a reduced acetylcholine concentration.
Acetylcholine receptors are discovered on the musculature, brain and heart.
The impact on the musculature results in the known unpredictable gait.
The heart, in turn, beats slower.
In addition, the unsafe motions most likely also result from a decrease in blood flow in the cerebellum, which is accountable for the course and coordination of the motor system.
Alcohol triggers an increase in dopamine and therefore a favorable impact on the body’s brain reward system in addition to an enhanced mood
Serotonin and norepinephrine
Alcohol triggers a decrease in the neurotransmitters serotonin and norepinephrine.
This increases aggressive and depressive behavior.
Endorphins and enkephalins
Increased alcohol consumption results in a boost in endorphins and enkephalins.
This boost triggers a so-called happiness and ecstasy.
Alcohol causes a decline of endogenous glutamate.
As a result, there is a cognitive problems and impaired memory function.
The potentiating result of alcohol on the inhibitory GABA receptor is especially well developed.
This causes hindered discomfort understanding and experience.
From 2 per mill alcohol in the blood exceed the indications of anesthesia, in alcoholics, however, this limit can shift noticeably upwards.
Fact 2: Alcohol injures nerves and nervous system
The worst changes in the nerve system due to regular alcohol intake are polyneuropathy, Wernicke’s encephalopathy and Korsakoff’s psychosis.
In addition to diabetes mellitus, chronic alcohol abuse is the leading reason for peripheral polyneuropathy. Polyneuropathy is a normal neuropathic discomfort or so-called nerve discomfort.
Normally, neuropathic pain is caused by injury or damage to neurons and/ or nerves.
Polyneuropathy is damage to thin nerve fibers (so-called small fibers) and distal axonopathy.
This leads to so-called paraesthesia (unpleasant, in some cases uncomfortable physical sensations with tingling, numbness, falling asleep limbs, cold and heat perception disorders) and discomfort initially on the hands and feet.
Targeted therapy of polyneuropathy is possible, inter alia, by the so-called little fiber matrix stimulation
Reality 3: Alcohol as a trigger or trigger factor of a migraine
In migraine, alcohol likewise has an unfavorable effect since of the vasodilator impact.
In 20-30%of migraine sufferers, alcohol is a safe trigger and frequently enough already a glass.
Some individuals understand that wines or specific types of wine and champagne frequently cause migraines.
Important: Alcohol or vascular modifications are not the reason for a migraine attack however an essential trigger or so-called trigger aspect.
Intriguing in this context is also that typically not just the alcohol plays a role, however especially the time of day or time at which the alcohol is drunk.
So there are often individuals in which sparkling wine after 20 o’clock without repercussions, in the morning after a champagne breakfast or in the early afternoon in the approval of an associate, however, highly likely a migraine attack is triggered.
Fact 4: Changed fluid balance after “soaked” night makes headache
Alcohol changes the fluid balance.
Specifically after a “night of drinking” you lose noticeably more fluid than you take.
The reason for this is the decreased release of the so-called antidiuretic hormone (ADH).
This hormone guarantees that the body maintains water, so you require less to the restroom.
Since alcohol hinders the release, you need to leave more water and there is an absence of fluids in the body to dehydration.
This absence of fluid is frequently straight accountable for headaches.
In addition, the absence of ADH can also negatively impact the brain fluid.
The brain, which is generally surrounded by fluid, in turn, is delicate to movement and may ultimately cause headaches.
Fact 5: Poisonous substances after a night of drenching also cause headaches
Alcohol is broken down in the liver.
This produces a hazardous compound, the so-called. Acetaldehyde, which in turn is converted to ethanol.
These toxic intermediates/ final product cause nausea and headache.
Of vital importance for this change or the destruction of alcohol is the enzyme alcohol dehydrogenase.
The quantity of this enzyme varies from person to person and identifies how quickly the intoxicated alcohol in the body is broken down.
How much alcohol a person tolerates depends on this element (but likewise on weight, whether you consumed something in the past, etc.).
It is understood that approximately 50%of the Japanese, Chinese and Vietnamese, however also some aboriginal individuals (eg
Aborigines in Australia) often have low levels of alcohol dehydrogenase in the body and hence “endure” less alcohol and quicker get a so-called flush syndrome (red face).
In principle, ladies have less of the alcohol-degrading enzymes than males.
In the fermentation procedure, the so-called Begleitalkohole (or also called Fuselalkohole) are produced in very little amounts.
They are harmful and are broken down more gradually than routine alcohol, so they still have an impact on the next day.
Accompanying alcohols are responsible for the devastating impacts, including headaches, and have a negative impact on the heart, liver, kidneys, and nervous system.
In addition to headaches, they also trigger a transformed pain level of sensitivity or level of sensitivity.
Truth 6: 1.3 million Germans are alcohol dependent and 70,000 pass away each year
About 1.3 million people in Germany depend on alcohol, according to the Federal Government Drug Commissioner, and more than nine million drink alcohol “in a risky state”.
Another figure: One in five patients admitted to a healthcare facility has persistent alcoholic abuse.
In Germany there are nearly 25,000 members of the Anonymous Alcoholics, who are on average 60 years of ages and hence live much shorter than the average (Source: Confidential Alcoholics).
Withdrawal signs such as trembling, fast heartbeat, hypertension, anxiety, and often head and body aches, are brought on by the abrupt cessation of persistent heavy alcohol usage.
Lots of alcoholics regularly have head and body aches.
In overall, over 70,000 individuals in Germany pass away each year from alcohol abuse.
Table: Intense impacts of alcohol on our body or organs
Reality 7: It was not possible without alcohol
Numerous centuries before Christ, alcoholic beverages (chemical name: ethyl alcohol) were used for anesthesia and pain relief.
Even Hippocrates used alcohol in order not to bow to the “dreadful wicked discomfort” without resistance.
The Romans intentionally started to utilize alcohol for medical functions, for instance in the control of illness, stone diseases and amputations.
Caesar’s soldiers needed to consume a gallon of white wine a day to prevent infectious illness, and the very first “professional” paramedics constantly had high-proof alcohol for pain control on the battleground.
The discomfort was typically just anesthetized, but the disease was not treated.
In addition, alcohol usage delays the recovery process.
The breakdown of alcohol consumes energy that the body needs to get well.
The Italian doctor and bishop Theodoric of Lucca developed for the purpose of surgical pain decrease sponges that were soaked with opium, mandragora and/ or alcohol.
Until the Middle Ages, alcohol and not occasionally the chewing of coca leaves was considered the only method to lower discomfort during a surgery.
Specifically patients with persistent discomfort see in the excessive alcohol usage a way out of their suffering.
But here, too, alcohol is only a hazardous symptom control. Today, chronic back pain without alcohol must be dealt with as part of a multimodal discomfort treatment.
Truth 8: Alcohol discomfort in Hodgkin’s lymphoma (deadly kind of cancer)
After consuming alcohol, enlarged lymph nodes might trigger pain (so-called alcohol discomfort), which is relatively rare, but then relatively normal of Hodgkin’s lymphoma (malignant lymphoid cancer).
In these cases, it is a common early symptom and is described in this kind for no other illness so far.
The causes of alcohol discomfort in Hodgkin’s lymphoma are still unclear.
However, clients frequently describe that they experience alcohol at the very first sip and then typically drop weight again really quickly.
If it comes over numerous weeks to this alcohol discomfort and you might still feel enlarged lymph nodes (usually in the neck area), so you should urgently see a medical professional.